![]() Of note, 56% of adults ≥45 years of age were classified as being in stage A (risk factors) or B (asymptomatic ventricular dysfunction). Survival at 5 years was 99% in stage 0, 97% in stage A, 96% in stage B, 75% in stage C, and 20% in stage D.Ĭonclusions- The present study provides prevalence estimates and prognostic validation for HF staging in a community cohort. Mean B-type natriuretic peptide concentrations (in pg/mL) increased by stages: stage 0=26, stage A=32, stage B=53, stage C=137, and stage D=353. In the cohort, 32% were stage 0, 22% stage A, 34% stage B, 12% stage C, and 0.2% stage D. Participants were classified by medical record review, symptom questionnaire, physical examination, and echocardiogram as follows: stage 0, healthy stage A, HF risk factors stage B, asymptomatic cardiac structural or functional abnormalities stage C, HF symptoms and stage D, severe HF. Methods and Results- A population-based, cross-sectional, random sample of 2029 Olmsted County, Minnesota, residents aged ≥45 years was identified. ![]() We sought to estimate HF stage prevalence in the community and to measure the association of HF stages with mortality. The prevalence of HF stages and their association with mortality are unknown. An American Heart Association/American College of Cardiology staging classification of HF has been developed to emphasize early detection and prevention. Customer Service and Ordering Informationīackground- Heart failure (HF) is a progressive disorder associated with frequent morbidity and mortality.Stroke: Vascular and Interventional Neurology.Journal of the American Heart Association (JAHA).Circ: Cardiovascular Quality & Outcomes.Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB).
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